LipoFlush - How Does it Work?

Choline and Carnitine – the Dynamic Duo for Fat Loss

Choline and carnitine are commonly used nutritional supplements, usually used alone or in combination and usually for the purposes of fat loss. Carnitine is essential for fatty acid transport and proper muscle function, and some studies have shown that carnitine supplementation improves exercise performance³. Choline is a lipotropic agent that prevents deposition of fat in the liver. It is an essential nutrient for humans by giving cell membranes structural strength and providing structure to cell membranes and is involved in the signaling across this membrane as well as synthesis and release of the neurotransmitter acetylcholine. Like carnitine, choline supplementation may also improve physical performance⁴.

The possible synergistic interaction between carnitine and choline has been known for several years. A study on rats published a few years ago clearly showed that choline in combination with caffeine plus carnitine resulted in a significant conservation of carnitine and augmented exercise performance and promoted fatty acid oxidation as well as disposal in urine⁵. As well, the use of the three supplements resulted in two other beneficial effects, a decrease in blood triglycerides and an increase in the triglyceride content of skeletal muscles. Since muscle fat is used to supply energy to exercising muscles, and actually increases muscle size, much like glycogen, this is a whole different thing to increasing fat in subcutaneous skin and other fatty areas of the body. The increase in intramuscular fat also helps endurance and recovery and would be useful on any diet.

But there’s more to the story. A new study has shown that choline and carnitine supplementation with or without exercise alters carnitine status, body fat and biochemical markers of fat oxidation in humans⁶. In this study nineteen women were placed in three groups: 1) placebo, choline or carnitine preloading period of 1 wk followed by 2) supplementation with choline plus carnitine during wk 2-wk 3 and 3) all groups exercised in wk 3.

There were several interesting results of this study outlining the effects of choline, and choline plus carnitine supplementation. Without going into all the details the study showed that the choline-induced decrease in serum and urinary carnitine is buffered by carnitine preloading, and these supplements shift tissue partitioning of carnitine that favors fat mobilization, incomplete oxidation of fatty acids and disposal of their carbons in urine as acylcarnitines in humans.

Flushing out fat in the urine has another interesting and useful effects for those trying to lose body fat. Flushing out fat in the form of acylcarnitines acts as an osmotic diuretic and increases urine flow, in some people more than others. As such, LipoFlush, along with its effects on appetite and fat loss, may be effective in decreasing fluid retention, a problem often seen in people dieting.

For women there may also be an added benefit in that LipoFlush may be useful in relieving the symptoms of PMS. That’s because fluid retention can worsen the symptoms of the premenstrual syndrome (PMS). Women with severe symptoms may experience increased irritability and decreased ability to cope with everyday stresses during the premenstrual phase - they often compensate by eating more. In these women the weight gain is due to a combination of fluid retention and increased caloric intake.

You can minimize fluid retention by cutting down on salt intake - avoiding foods heavy in salt and use of the salt shaker, and in the more severe cases using medication such as prescription diuretics. However, LipoFlush, because of its diuretic like action, may naturally decrease fluid retention and improve symptoms.

The bottom line is that choline and carnitine supplementation increased fat loss by both increasing the breakdown and burning of body fat and, interestingly enough, actually flushing fat (in the form of acylcarnitines, which are actually chunks of fatty acids combined with carnitine) into the urine and out of the body. In this latter action it’s as close as you can get to being the nutritional supplement equivalent of liposuction. LipoFlush will literally flush the fat right out of your body.

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